Natural anitsense transcripts in Plasmodium falciparum clinical isolates

ABSTRACT: Mechanisms regulating gene expression in malaria parasites are not well understood. Little is known about how this parasite regulates its gene expression during transition from one developmental stage to another and in response to various environmental conditions. Parasites in a diseased host face environments which differ from the static, well adapted in vitro conditions in culture. Parasites thus need to adapt quickly and effectively to these conditions by establishing transcriptional states which is best suited for better survival. With the discovery of natural antisense transcripts (NATs) in this parasite and considering the various proposed mechanisms by which NATs might regulate gene expression, it has been speculated that these might be playing a critical role in gene regulation. We

ORGANISM(S): Plasmodium falciparum

SUBMITTER: Ashis Das 

PROVIDER: E-GEOD-44921 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress