The purine metabolite allantoin enhances abiotic stress tolerance through synergistic activation of abscisic acid metabolism

ABSTRACT: Purine catabolism is regarded as a housekeeping function that remobilizes nitrogen for plant growth and development. However, emerging evidence suggests that certain purine metabolites might contribute to stress protection of plants. Here, we show that in Arabidopsis, the intermediary metabolite allantoin plays a role in abiotic stress tolerance via activation of abscisic acid (ABA) metabolism. The aln loss-of-function of ALN, encoding allantoinase, results in increased allantoin accumulation, genome-wide up-regulation of stress-related genes, and enhanced tolerance to drought-shock and osmotic stress in aln mutant seedlings. This phenotype is not caused by a general response to purine catabolism inhibition, but rather results from a specific effect of allantoin. Allantoin activates ABA pr

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Atsushi Sakamoto 

PROVIDER: E-GEOD-44922 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress