Testing rescue of AR signaling by ectopic expression of mutant AR allele in the presence of MDV-3100

ABSTRACT: Genetically engineered LNCaPs overexpressing various AR alleles were treated with 0.1% DMSO or 10uM MDV3100 for 24h prior to collection This experiment is designed to see if expressing the F876L/T877A mutant AR can rescue AR signaling in the presence of MDV3100 Engineered lines were seeded in 6-well plates for 3d with 100ng/ml doxycycline prior to treatment with 0.1% DMSO or 10uM MDV3100 for 24h

ORGANISM(S): Homo sapiens

SUBMITTER: Joshua Korn 

PROVIDER: E-GEOD-44924 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress