Evaluation of hepatic gene expression profiles during androgen exposure in female mosquitofish

ABSTRACT: The Eastern Mosquitofish (Gambusia holbrooki) is a non-model species with the potential for development of biomarkers of endocrine disrutpting chemical (EDC) exposure due to its androgen-driven secondary sexual characteristics. While G. holbrooki have been utilized in the field as bioindicator organisms EDC exposure in areas impacted by pulp and paper mills, the lack of molecular tools and general understanding of how G. holbrooki are impacted by androgen exposure hinder the use of this organism as a widespread tool for the evaluation of these chemicals in the environment. While traditional gene-by-gene approaches have provided a list of genes that may be appropriate for developing into biomarkers of androgen exposure, a more inclusive method could provide more rapid and expansive determin

ORGANISM(S): Gambusia holbrooki

SUBMITTER: Erica Brockmeier 

PROVIDER: E-GEOD-45261 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress