Genome Wide Association identifies Novel Loci Involved Fungal Communication

ABSTRACT: Understanding how genomes encode complex cellular and organismal behaviors is an outstanding challenge of modern genetics. Unlike classical screening methods, analysis of the genetic variation that occurs naturally in wild populations can enable rapid, genome-scale trait mapping with a medium-throughput experimental design. Here we describe the results of the first genome-wide association analysis (GWAS) of a microbial eukaryote, using wild isolates of the filamentous fungus Neurospora crassa. We transcriptionally profiled each of 112 individuals collected in Louisiana and used RNA-seq data to genotype each strain at thousands of genetic loci genome-wide. We used these genotypes in a mapping analysis of microbial communication. In N. crassa, germinated asexual spores (germlings) sense t

ORGANISM(S): Neurospora crassa

SUBMITTER: Charles Hall 

PROVIDER: E-GEOD-45406 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress