Gene expression of E. coli in continuous culture during adaptation to artificial sunlight

ABSTRACT: E. coli growing in continuous culture under continuous UVA irradiation exhibits growth inhibition with a subsequent adaptation to the stress. Transcriptome analysis was performed during transient growth inhibition and in the UVA light-adapted growth state. The results indicate that UVA light induces stringent response and an additional response that includes the upregulation of the synthesis of valine, isoleucine, leucine, phenylalanine, histidine and glutamate. The induction of several SOS response-genes strongly points to DNA damage as a result of UVA exposure. The involvement of oxidative stress was observed with the induction of ahpCF. Taken together it supports the hypothesis of the production of reactive oxygen species by UVA light. In the UVA-adapted cell population strong rep

ORGANISM(S): Escherichia coli

SUBMITTER: Michael Berney 

PROVIDER: E-GEOD-4569 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress