Changes in gene expression profiles of circulating B cells after influenza vaccination in healthy human subjects

ABSTRACT: Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. In B cells, 90% of transcriptomic variation in subjects who received influenza vaccine within the previous three years was explained by a single temporal pattern unique to the individual. A common set of 742 genes was strongly correlated with the migration of differentiating plasma cell subtypes. Five subjects, 11 time points per subject (pre-vaccination and daily for 10 days post-vaccination)

ORGANISM(S): Homo sapiens

SUBMITTER: Stephen Welle 

PROVIDER: E-GEOD-45734 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress