Murine FAE and VE in BALB/cA mice

ABSTRACT: M cells in the follicle-associated epithelium (FAE) of Peyer’s patches (PPs) serve as a main portal for external antigens. Limitation in the number of M cells has hampered identification of their specific molecules until recently. Efforts by us as well as others has gradually unraveled the molecular mechanisms for the development and differentiation of M cells. However, molecular mechanisms of antigen transcytosis and M cell differentiation were not fully elucidated. Recent studies reported that small non-coding RNAs including microRNA (miRNA) regulate gene expression that controls various biological processes such as cellular differentiation and functions. In fact, intestinal epithelial miRNAs play a critical role in goblet cell differentiation and maturation. However, the expression and

ORGANISM(S): Mus musculus

SUBMITTER: Gaku Nakato 

PROVIDER: E-GEOD-46264 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress