Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs)

ABSTRACT: RNA-sequencing of SSP RNA from patients with serrated polyposis syndrome identifies VSIG1 and MUC17 as potential diagnostic markers for SSPs 5' capped RNA from seven ascending SSPs, six patient matched uninvolved right colon and two normal right colon samples was used for RNA sequencing (15 samples total)

ORGANISM(S): Homo sapiens

SUBMITTER: Don Delker 

PROVIDER: E-GEOD-46513 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers.

Delker Don A DA   McGettigan Brett M BM   Kanth Priyanka P   Pop Stelian S   Neklason Deborah W DW   Bronner Mary P MP   Burt Randall W RW   Hagedorn Curt H CH  

PloS one 20140212 2

<h4>Background</h4>Sessile serrated adenomas/polyps (SSA/Ps) may account for 20-30% of colon cancers. Although large SSA/Ps are generally recognized phenotypically, small (<1 cm) or dysplastic SSA/Ps are difficult to differentiate from hyperplastic or small adenomatous polyps by endoscopy and histopathology. Our aim was to define the comprehensive gene expression phenotype of SSA/Ps to better define this cancer precursor.<h4>Results</h4>RNA sequencing was performed on 5' capped RNA from seven SS  ...[more]

Similar Datasets

Transcriptomics Gene signature in sessile serrated polyps identifies colon cancer subtype
2016-04-08 | GSE76987 | GEO
Unknown Molecular Biomarkers of Sessile Serrated Adenoma/Polyps.
| S-EPMC6970553 | biostudies-literature
Unknown Hyper-Methylated Loci Persisting from Sessile Serrated Polyps to Serrated Cancers.
| S-EPMC5372551 | biostudies-literature
Transcriptomics Gene expression analysis of microvesicular hyperplastic polyps and sessile serrated polyps/adenomas
2013-07-09 | E-GEOD-43841 | biostudies-arrayexpress
Genomics Small RNA sequencing of sessile serrated polyps identifies miRNA profile associated with colon cancer
2018-10-18 | GSE118504 | GEO
Transcriptomics Mouse Synovial Sarcoma Models
2016-07-01 | E-GEOD-71843 | biostudies-arrayexpress
Unknown Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.
| S-EPMC4941619 | biostudies-literature
Transcriptomics Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines
2016-07-01 | E-GEOD-71541 | biostudies-arrayexpress
Unknown The proto CpG island methylator phenotype of sessile serrated adenomas/polyps.
| S-EPMC6342079 | biostudies-literature
Unknown Prevalence and Clinical Features of Sessile Serrated Polyps: A Systematic Review.
| S-EPMC8653879 | biostudies-literature