Transcriptional profiling of Pseudomonas aeruginosa PAO1161 strain and its parA and parB mutants

ABSTRACT: Representatives of two families of bacterial Par proteins, ParA and ParB, are encoded by the majority of bacterial chromosomes in the close vicinity of oriC. ParA(Soj) and ParB(Spo0J) proteins of Pseudomonas aeruginosa are both important for optimal growth, nucleoids segregation, cell division and different types of motility. Comparative transcriptome analysis of parAnull, parBnull mutants versus parental PAO1161 strain of P. aeruginosa demonstrated global changes in genes expression pattern in logarithmic phase of planktonic cultures grown on rich medium. The set of genes that were similarly regulated in both mutant strains as compared to the wild-type strain as well as two sets of genes uniquely affected in the particular mutant were defined suggesting that ParA and ParB may act in commo

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Aneta Bartosik 

PROVIDER: E-GEOD-47031 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress