Expression of miR-196a in Huntington's disease transgenic (HD) mice

ABSTRACT: We intend to screen altered genes after overexpression of miR-196a in HD transgenic mice. Two transgenic mouse lines were used in this study, including HD transgenic mice and HD transgenic mice overexpressing miR-196a. The mice were all at approximate 12 months of age. At this point, HD transgenic mice showed severve motor dysfunctions, whereas HD transgenic mice overexpressing miR-196a displayed mild motor dysfunctions. We used the striatum tissues from 2 HD transgenic mice and 3 HD transgenic mice overexpressing miR-196a. The mice were all at approximate 12 months of age. Two technique repeats were performed for each sample.

ORGANISM(S): Mus musculus

SUBMITTER: Shang-Hsun Yang 

PROVIDER: E-GEOD-47500 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress