Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction [Agilent array]

ABSTRACT: We report that acetylation of H4K16 is a new marker of active enhancers and that some enhancers are marked by H3K4me1, MOF and H4K16ac but not by acetylated H3K27 or p300, suggesting that they are novel p300-independent regulatory elements. Gene expression in undifferentiated 46c (sox1-gfp) ES cells, and gfp FACS sorted cells after 5 days of differentiation to neural progenitor cells with NB27 and Neuro2 medium supplements. 3 biological replicates were performed for each sample.

ORGANISM(S): Mus musculus

SUBMITTER: Gillian Taylor 

PROVIDER: E-GEOD-47716 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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