Human adult white matter progenitor cells are multipotent neuroprogenitors identical to adult hippocampal progenitors

ABSTRACT: Adult neural progenitor cells (aNPCs) are a potential autologous cell source for cell replacement in neurologic diseases such as Parkinson’s disease or stroke or for cell-based gene therapy for neurometabolic diseases. Easy accessibility, long-term expandability and detailed characterization of NPC properties are important requisites for their future translational/clinical applications. aNPC can be isolated from different regions of the adult human brain including the accessible subcortical white matter (aNPCWM), but systematic studies comparing long-term expanded aNPCWM with aNPC from neurogenic brain regions to check for their NPC characteristics and performance are not available. Freshly isolated cells from subcortical white matter and hippocampus (aNPCHIP) expressed oligodendroc

ORGANISM(S): Homo sapiens

SUBMITTER: Marcos Araúzo-Bravo 

PROVIDER: E-GEOD-47921 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress