Effects on the hepatic transcriptome due to caloric restriction are not altered by milking frequency

ABSTRACT: The ruminant liver has multiple roles in the dairy cow and many of these are crucial in nutrient supply during lactation. Reduced feed intake alters the expression of many genes and pathways in the liver, inducing a period of negative energy balance. Once-daily milking is a management strategy to reduce the effects of periods of negative energy balance so the objective of this study was to determine if once-daily milking altered hepatic gene transcription during a period of negative energy balance induce by caloric restriction. Multiparous Holstein-Friesian and Holstein-Friesian x Jersey cows (n = 120) were grazed on pasture and milked twice daily (2X) from calving until 34 ± 6 days in milk (mean ± standard deviation). Cows were then allocated to one of four treatments in a 2 x 2 factorial

ORGANISM(S): Bos taurus

SUBMITTER: Talia Grala 

PROVIDER: E-GEOD-47925 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress