Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Emma Laing
PROVIDER: E-GEOD-48113 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Archer Simon N SN Laing Emma E EE Möller-Levet Carla S CS van der Veen Daan R DR Bucca Giselda G Lazar Alpar S AS Santhi Nayantara N Slak Ana A Kabiljo Renata R von Schantz Malcolm M Smith Colin P CP Dijk Derk-Jan DJ
Proceedings of the National Academy of Sciences of the United States of America 20140121 6
Circadian organization of the mammalian transcriptome is achieved by rhythmic recruitment of key modifiers of chromatin structure and transcriptional and translational processes. These rhythmic processes, together with posttranslational modification, constitute circadian oscillators in the brain and peripheral tissues, which drive rhythms in physiology and behavior, including the sleep-wake cycle. In humans, sleep is normally timed to occur during the biological night, when body temperature is l ...[more]