Ontology highlight
ABSTRACT:
ORGANISM(S): Sus scrofa
SUBMITTER: Denise Kelly
PROVIDER: E-GEOD-48125 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
American journal of physiology. Gastrointestinal and liver physiology 20131024 1
Preterm birth, bacterial colonization, and formula feeding predispose to necrotizing enterocolitis (NEC). Antibiotics are commonly administered to prevent sepsis in preterm infants, but it is not known whether this affects intestinal immunity and NEC resistance. We hypothesized that broad-spectrum antibiotic treatment improves NEC resistance and intestinal structure, function, and immunity in neonates. Caesarean-delivered preterm pigs were fed 3 days of parenteral nutrition followed by 2 days of ...[more]