Expression data analysis of murine pulmonary cryptococcosis induced by C. gattii

ABSTRACT: Our previous investigation indicated that high-virulence C. gattii (C. gattii TIMM 4097) tend to reside in the alveoli, whereas low-virulence C. gattii (C. gattii TIMM 4903) tend to be washed out from the alveoli and move into the central side of the respiratory system. To test this hypothesis, we performed microarray assay. C. gattii TIMM 4097 and C. gattii TIMM 4903 were prepared for the study. The mice were anesthetized and the spore suspension was intratracheally injected into each mouse. Mice were sacrificed 15 days after the infection and then examined. Lung of the mice infected with C. gattii TIMM 4097 and C. gattii TIMM 4903 and normal controls were obtained (n=3, respectively. RNA targets preparation was performed according to the manufacturer's protocol using GeneChip(R) 3' IVT E

ORGANISM(S): Mus musculus

SUBMITTER: Yoichiro Okubo 

PROVIDER: E-GEOD-48595 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress