Functional genomic analysis of a commercial wine strain of Saccharomyces cerevisiae under differing nitrogen conditions.

ABSTRACT: DNA microarray analysis was used to profile gene expression in a commercial isolate of Saccharomyces cerevisiae grown in a synthetic grape juice medium under conditions mimicking a natural environment for yeast: High-sugar and variable nitrogen conditions. The high nitrogen condition displayed elevated levels of expression of genes involved in biosynthesis of macromolecular precursors across the time course as compared to low-nitrogen. In contrast, expression of genes involved in translation and oxidative carbon metabolism were increased in the low-nitrogen condition, suggesting that respiration is more nitrogen-conserving than fermentation. Several genes under glucose repression control were induced in low-nitrogen in spite of very high (17%) external glucose concentrations, but there was

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Joe DeRisi 

PROVIDER: E-GEOD-4887 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress