Antiviral signaling mediates inhibition of RNAi in mammalian cells

ABSTRACT: Analysis of the interferon response (specifically interferon stimulated genes-ISGs) in human DLD-1 cells that have decreased microRNA expression due to a exon mutation in Dicer. The hypothesis tested in the present study is that ISGs are particularly suspectible to microRNA regulation. Total RNA obtained from both WT and microRNA hypmorphic DLD-1 cells after 3, 8, and 24 hours post interferon treatment

ORGANISM(S): Homo sapiens

SUBMITTER: Chris Sullivan 

PROVIDER: E-GEOD-49835 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress