Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

12 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [brain]

ABSTRACT: Genome wide DNA methylation profiling of 4 human tissues of various ages: 78 samples from Brodmann area 19 of the cerebral cortex.The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode included for batch normalization 1ug of genomic DNA was bisulfite converted using EZ-96 DNA Methylation Kit from ZymoResearch, and hybridized to beadchips according to Illumina Infinium 27k Human DNA methylation standard procedures

ORGANISM(S): Homo sapiens

SUBMITTER: Devin Absher

PROVIDER: E-GEOD-49905 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [muscle]

Project description:Genome wide DNA methylation profiling of 4 human tissues of various ages: 51 vastus lateralis samples.The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode provided for batch normalization 500ng of genomic DNA was bisulfite converted using EZ-96 DNA Methylation Kit from ZymoResearch, and hybridized to beadcheaps according to Illumina Infinium 27k Human DNA methylation standard procedures.

2013-08-16 | E-GEOD-49908 | biostudies-arrayexpress

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [kidney]

Project description:Genome wide DNA methylation profiling of 4 human tissues of various ages: 83 samples of normal adjacent resected kidney tissue .The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode provided for batch normalization 1ug of genomic DNA was bisulfite converted using EZ-96 DNA Methylation Kit from ZymoResearch, and hybridized to beadcheaps according to Illumina Infinium 27k Human DNA methylation standard procedures

2013-08-16 | E-GEOD-49907 | biostudies-arrayexpress

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [blood]

Project description:Genome wide DNA methylation profiling of 4 human tissues of various ages: 71 human buffy coat samples. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode provided for batch correction Buffy coats obtained from Conversant Bio and genomic DNAs isolated by Agencourt Genfind v2; 1ug of genomic DNA was bisulfite converted using EZ-96 DNA Methylation Kit from ZymoResearch; samples hybridized to beadchips according to Illumina Infinium 27k Human DNA methylation standard procedures

2013-08-16 | E-GEOD-49904 | biostudies-arrayexpress

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [brain]

Project description:Genome wide DNA methylation profiling of 4 human tissues of various ages: 78 samples from Brodmann area 19 of the cerebral cortex.The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode included for batch normalization

2013-08-16 | GSE49905 | GEO

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [muscle]

2013-08-16 | GSE49908 | GEO

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [blood]

2013-08-16 | GSE49904 | GEO

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [kidney]

2013-08-16 | GSE49907 | GEO

DNA methylation screening identifies driver epigenetic events of cancer cell survival.

Project description:Genome wide DNA methylation profiling of colon adenocarcinoma cell line HCT116 wild type and with a genetic disruption of DNMT3B and DNMT1 (DKO). The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. For this study, we used two DKO subclones, DKO8 and DKO1, which retain approximately 45% and 5% of the HCT116 wild type global DNA methylation levels, respectively Bisulphite converted DNA from the 3 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2

2012-03-16 | E-GEOD-36534 | biostudies-arrayexpress

Aging effects on DNA methylation modules in blood tissue

Project description:Genome wide DNA methylation profiling of whole blood in schizophrenia patients and healthy subjects. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Raw data included 325 schizophrenia patients (2) and 394 controls (1) from Dutch descent. One sample was excluded since it was a bipolar patient, indicated by 3 in diseaseStatus column. The column used_in_analysis shows the samples that were used in our study. The excluded samples failed quality control. Normalized data are also included in the non_normalized.txt (i.e. AVG_Beta column). Bisulphite converted DNA from 720 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip [Publication: Horvath et al., Genome Biology, Special Edition]

2012-09-21 | E-GEOD-41037 | biostudies-arrayexpress

Epigenome analysis of primary MCL

Project description:Genome wide DNA methylation profiling of primary MCL. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Bisulphite converted DNA from the 132 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2

2015-12-31 | E-GEOD-45253 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data