Adaptation of Propionibacterium freudenreichii to the colon environment

ABSTRACT: Mechanisms allowing P. freudenreichii adaptation to digestive stresses have been only studied in vitro so far. Our aim was therefore to study P. freudenreichii metabolic adaptation to intra-colonic conditions in situ. We maintained a pure culture of P. freudenreichii CIRM-BIA1, contained in a dialysis bag, within the colon of vigilant piglets during 24 hours. A transcriptomic analysis identified the metabolic pathways induced by this environment, in comparison with control propionibacteria maintained in spent culture medium. 12 cutures in a dialysis bag in the colon of piglets during 24H compared to 12 cultures propionibacteria maintained in spent culture medium

ORGANISM(S): Propionibacterium freudenreichii

SUBMITTER: HM-CM-)lM-CM-(ne Falentin 

PROVIDER: E-GEOD-50089 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress