Characterization of chromosomal architecture in Arabidopsis thaliana by Chromosome Conformation Capture

ABSTRACT: Background: The packaging of long chromatin fibres in the nucleus poses a major challenge, as it must fulfil both physical and functional requirements. Until recently, insight into the chromosomal architecture of plants was mainly provided by cytogenetic studies. Complementary to these analyses, chromosome conformation technologies promise to refine and improve our view on chromosomal architecture and to provide a more generalised description of nuclear organization. Results: Employing circular chromosome conformation capture (4C), this study describes chromosomal architecture in Arabidopsis nuclei from a genome-wide perspective. Surprisingly, the linear organisation of chromosomes is reflected in the genome-wide interactome. In addition, we studied the interplay of the interactome and ep

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Stefan Grob 

PROVIDER: E-GEOD-50181 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress