Exon Array Data for Colerectal Tumor and Normal Samples

ABSTRACT: Exon-Level and Gene-Level Expression analysis of Tumor and Normal Samples The effect of somatic copy number alterations at the functional level can be analyzed by looking into the expression pattern of the affected genes. The task of identifying the M-bM-^@M-^XaffectedM-bM-^@M-^Y genes is facilitated by robust algorithms that carry out sensitive and confident localization of the targets of somatic copy number alterations in cancer. We had earlier identified 144 genes by GISTIC analysis that were potential targets of SCNAs. In this study we report our findings based on exon level analysis of these genes. Only a subset of these genes was found to have significant changes in expression levels. 8/24 genes were found to have fold change value >1.5 and 3 of them were reported as novel in their a

ORGANISM(S): Homo sapiens

SUBMITTER: Sathish Periyasamy 

PROVIDER: E-GEOD-50421 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress