Gene (mRNA) expression profiling in frontal cortex of ethanol-treated mice

ABSTRACT: Analysis of early stages of alcohol dependence at the gene expression level. The hypothesis tested in the present study was that ethanol-treatment impact gene expression in a mouse model of high ethanol consumption. Results provide important information of genes and pathways being affected by ethanol actions in the mouse frontal cortex. Total RNA obtained from frontal cortex from mice treated with 20% ethanol solution for 20 days. Control group is composed of untreated animals. Frontal cortex (FCtx) tissue was dissected to produce a 2-mm coronal section from the most rostral portion of the mouse brain devoid of olfactory bulbs (coordinates Bregma +1.56 to +3.56). The dorsal part of this coronal section, cut immediately above the forceps minor of the corpus callosum as the anatomical landma

ORGANISM(S): Mus musculus

SUBMITTER: Yury Nunez 

PROVIDER: E-GEOD-50427 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress