MicroRNAs in bovine adipose tissue: genomic context, expression and function

ABSTRACT: MicroRNAs (miRNAs) are small non-coding RNAs found to regulate several biological processes including adipogenesis. Understanding adipose tissue regulation is critical for beef cattle as fat is an important determinant of beef quality and nutrient value . This study analyzed the association between genomic context characteristics of miRNAs with their expression and function in bovine adipose tissue. Twenty-four subcutaneous adipose tissue biopsies were obtained from eight British-continental crossbred steers at 3 different time points . Total RNA was extracted and miRNAs were profiled using a miRNA microarray with expression further validated by qRT-PCR. A total of 224 miRNAs were detected of which 155 were expressed in all steers (n=8), and defined as the core miRNAs of bovine subcutaneo

ORGANISM(S): Bos taurus

SUBMITTER: Josue Romao 

PROVIDER: E-GEOD-50489 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress