Gene expression analysis of RB1 knockdown in bone in response to radiation

ABSTRACT: The role of RB1 in response to radiation was examined in human osteoblasts. We demonstrate that RB1 induced SASP genes, a response which was attenuated in RB1 knockdown osteoblasts. Subconfluent hOB shEV and shRB1 cells were irradiated at 4 Gy using a 137Cesium source at a dose rate of 1.7 min/Gy and cell pelllets collected 0, 2, 4, 8, 16 and 24 hrs after irradiation.

ORGANISM(S): Homo sapiens

SUBMITTER: Maya Kansara 

PROVIDER: E-GEOD-50532 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress