Spatiotemporal embryonic transcriptomics reveals the evolutionary history of the endoderm germ layer

ABSTRACT: The germ layer concept has been one of the foremost organizing principles in developmental biology, classification, systematics and evolution for 150 years. Of the three germ layers, the mesoderm is found in bilaterian animals but is absent in species in the phyla Cnidaria and Ctenophora, which has been taken as evidence that the mesoderm was the final germ layer to evolve. The origin of the ectoderm and endoderm layers, however, remains unclear with models supporting the antecedence of each as well as a simultaneous origin. We hypothesized that global analysis of gene expression in each layer throughout development may resolve the early events of animal evolution. Here, we determine the temporal and spatial components of gene expression spanning embryonic development for all C. elegans ge

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Itai Yanai 

PROVIDER: E-GEOD-50548 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress