Genomic localization of Cockayne syndrom B protein upon genotoxic stresses

ABSTRACT: Cockayne syndrome is an inherited premature aging syndrome associated with developmental and neurological disorders. Mutations in the genomic locus encoding CSB are associated with 80% Cockayne syndrome cases. CSB is invovled in relieving UV-induced and oxidative stree. To gain more insights into the fucntion of CSB under these stress, we use ChIP-seq to determine the genomic localization of CSB 1 hour after UV irradiation and menadione treatment. Genomic localization of CSB and remodeling deficient CSB∆N1

ORGANISM(S): Homo sapiens

SUBMITTER: Jieun Jeong 

PROVIDER: E-GEOD-50925 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress