Penicillium marneffei: Gene expression profiling of hyphal and yeast cells and during conidiation

ABSTRACT: Penicillium marneffei (Talaromyces marneffei) is an opportunistic human pathogen that can grow in a multicellular hyphal form at 25M-BM-0C or a unicellular fission yeast form at 37M-BM-0C, and can switch between these two forms in response to temperature. The yeast form is found in infected individuals and represents the pathogenic phase. In response to specific environmental cues, the hyphal form can undergo asexual development (conidiation) the produce a differentiated multicellular structure called a conidiophore which produces dormant spores (conidia). Inhaled conidia initiate infection. To identify genes that are M-bM-^@M-^Xphase or cell-state specificM-bM-^@M-^Y transcriptional profiling was performed with a custom microarray consisting of ~42% of the predicted P. marneffei genes and

ORGANISM(S): Talaromyces marneffei

SUBMITTER: Alex Andrianopoulos 

PROVIDER: E-GEOD-51109 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress