Age-related changes in microRNA levels in serum (mRNA)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Kevin Becker
PROVIDER: E-GEOD-51309 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Age-related changes in microRNA levels in serum.
Noren Hooten Nicole N Fitzpatrick Megan M Wood William H WH De Supriyo S Ejiogu Ngozi N Zhang Yongqing Y Mattison Julie A JA Becker Kevin G KG Zonderman Alan B AB Evans Michele K MK
Aging 20131001 10
MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by targeting specific mRNAs. Altered expression of circulating miRNAs have been associated with age-related diseases including cancer and cardiovascular disease. Although we and others have found an age-dependent decrease in miRNA expression in peripheral blood mononuclear cells (PBMCs), little is known about the role of circulating miRNAs in human aging. Here, we examined miRNA expression in human s ...[more]
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