Streptococcus mutans UA159; 10 mM Glucose Versus 100 mM Glucose
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ABSTRACT: Transcriptional Profiling of Streptococcus mutans UA159 Grown in Continuous Culture using TV Media Supplemented With 10 mM vs 100 mM Glucose. The genetic and phenotypic responses of Streptococcus mutans, an organism known to be strongly associated with the development of dental caries, to changes in carbohydrate availability were investigated. S. mutans UA159 or a derivative of UA159 lacking ManL, which is the EIIAB component (EIIABMan) of a mannose/glucose permease of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) and a dominant effector of catabolite repression, were grown in continuous culture to steady-state in conditions of excess (100 mM) or limiting (10 mM) glucose. Microarrays using RNA from S. mutans UA159 revealed that 174 genes were differentially expressed in res
ORGANISM(S): Streptococcus mutans UA159
SUBMITTER: Zachary Moye
PROVIDER: E-GEOD-51362 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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