Heterochronic meiotic misexpression in an interspecific yeast hybrid

ABSTRACT: Changes in gene regulation rapidly accumulate between species and may contribute to reproductive isolation through misexpression of genes in interspecific hybrids. Hybrid misexpression, defined by expression levels outside the range of both parental species, is thought to be a result of cis- and trans-acting regulatory changes that interact in the hybrid, or arise from changes in the relative abundance of various tissues or cell types due to defects in developmental. Here, we show that misexpressed genes in a sterile interspecific Saccharomyces yeast hybrid result from a heterochronic shift in the timing of the normal meiotic gene expression program. By tracking nuclear divisions, we find that S. cerevisiae initiates meiosis earlier than its closest known relative, S. paradoxus, yet both s

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Devjanee Swain Lenz 

PROVIDER: E-GEOD-51809 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress