Expression data from mesenchymal stromal cells isolated from the umbilical cord tissue (UCXM-BM-.) and cultivated in ATMP-compatible media

ABSTRACT: Standardization of MSC manufacturing is urgently needed to facilitate comparison of clinical trial results. Here, we compare gene expression of MSC generated by the adaptation of a proprietary method for isolation and cultivation of a specific umbilical cord tissue-derived population of Mesenchymal Stromal Cells (MSCs) The adaptation focused on different stages of production, from cell isolation steps to cell culturing and preservation. The origin and quality of reagents were considered and steps for avoiding microbiological and endotoxin contamination of the final cell product were implemented. Cell isolation efficiency, MSC surface markers and genetic profiles originating from the use of different medium supplements were compared. The ATMP-compliant UCXM-BM-. product was also cryopreserv

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Geffers 

PROVIDER: E-GEOD-51869 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress