Dataset Information


Transcriptomic analysis of WT and larp1 mutant 21 days old seedling at 20°C or following a heat stress (15 min at 38°C)

ABSTRACT: We report the identification of a heat-stress mediated mRNA decay in arabidopsis that is mediated by the XRN4 exonuclease and LARP1 RNA-binding protein. mRNA population in WT and larp1 mutant at 20C or 15 min at 38C

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Jean-Marc Deragon 

PROVIDER: E-GEOD-51879 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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XRN4 and LARP1 are required for a heat-triggered mRNA decay pathway involved in plant acclimation and survival during thermal stress.

Merret Rémy R   Descombin Julie J   Juan Yu-ting YT   Favory Jean-Jacques JJ   Carpentier Marie-Christine MC   Chaparro Cristian C   Charng Yee-yung YY   Deragon Jean-Marc JM   Bousquet-Antonelli Cécile C  

Cell reports 20131201 5

To survive adverse and ever-changing environmental conditions, an organism must be able to adapt. It has long been established that the cellular reaction to stress includes the upregulation of genes coding for specific stress-responsive factors. In the present study, we demonstrate that during the early steps of the heat stress response, 25% of the Arabidopsis seedling transcriptome is targeted for rapid degradation. Our findings demonstrate that this process is catalyzed from 5' to 3' by the cy  ...[more]

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