Nfatc1 Orchestrates Aging in Hair Follicle Stem Cells

ABSTRACT: Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by hair follicle stem cells (HFSCs). We used ChIP-seq to unfold genome-wide chromatin landscapes of Nfatc1 and dissect the biological relevence of its upstream BMP signaling in HFSC aging. Telogen quiescent hair follicle stem cells (HFSCs) were FACS-purified for ChIP-sequcencing.

ORGANISM(S): Mus musculus

SUBMITTER: Brice Keyes 

PROVIDER: E-GEOD-52328 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress