835np mutant vs wild-type

ABSTRACT: Transcriptional profiling of the M-NM-^T835np mutant vs the wild-type strain grown in BHI to OD600=0.5. An intimate linkage between the regulation of biofilm formation, stress tolerance and genetic competence exists in the dental caries pathogen Streptococcus mutans. We previously reported that the rcrRPQ genes, which encode ABC exporters (RcrPQ) and a MarR-family transcriptional regulator (RcrR) that represses the expression of the rcr operon, play a dominant role in regulation of development of genetic competence and connect competence with stress tolerance and (p)ppGpp production in S. mutans. Here we identify the region required for efficient RcrR binding to the rcr promoter region using purified recombinant RcrR (rRcrR) protein in electrophoretic mobility shift and fluorescence polari

ORGANISM(S): Streptococcus mutans

SUBMITTER: Sang-Joon Ahn 

PROVIDER: E-GEOD-52574 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress