Genome-wide nucleosome positioning is orchestrated by genomic regions associated with DNase I hypersensitivity in rice

ABSTRACT: Nucleosome positioning dictates the DNA accessibility for regulatory proteins, and thus is critical for gene expression and regulation. It has been well documented that only a subset of nucleosomes are reproducibly positioned (phased) in eukaryotic genomes. The most prominent example of phased nucleosomes is the context of genes, where phased nucleosomes flank the transcriptional starts sites (TSSs). It is unclear, however, what factors influence nucleosome phasing in regions that are not close to genes. We performed a combinational mapping of nucleosome positioning and DNase I hypersensitive sites (DHSs) across the rice genome. We discovered that DHSs located in a variety of contexts, both genic and intergenic, were flanked by strongly phased nucleosome arrays. Our results support the bar

ORGANISM(S): Oryza sativa

SUBMITTER: Yufeng Wu 

PROVIDER: E-GEOD-53027 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress