The expression profiling comparison of mice with Scap and Insig deletion from perinatal lung (E17.5-PN1)

ABSTRACT: In this study, we studied the genomic responses of the Insig and Scap deletion from perinatal lung. Through comprehensive data analysis and integration, time dependent effects of epithelial SCAP/INSIG/SREBP deletion and defined SCAP/INSIG/SREBP-associated genes, bioprocesses and downstream pathways were identified. Total lung RNA was isolated from Scapdelata/delta, Insig1/2delta/delta, and respective control littermates at E17.5, E18.5 and PN1 were used for mRNA expression profiling analysis (n=3 for each condition)

ORGANISM(S): Mus musculus

SUBMITTER: Yan Xu 

PROVIDER: E-GEOD-53397 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress