Long term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster

ABSTRACT: Recent studies have revealed key roles of non-coding RNAs in sex-related pathways, but little is known about the evolutionary forces acting on these non-coding RNAs. We used whole-genome tiling arrays to profile the transcriptome of Drosophila melanogaster tissues and found that 15% of male-biased transcribed fragments (transfrags) are intergenic non-coding RNAs (incRNAs), suggesting a potentially important role for incRNAs in sex-related biological processes. Statistical analysis revealed a paucity of male-biased incRNAs and coding genes on the X chromosome, suggesting that similar evolutionary forces could be affecting the genomic organization of both coding and non-coding genes. Expression profiling across germline and somatic tissues further suggests that both male meiotic sex chromoso

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Maria Vibranovski 

PROVIDER: E-GEOD-53421 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress