Sex-specific embryonic gene expression in species with newly evolved sex chromosomes

ABSTRACT: Sex chromosome dosage differences between males and females are a significant form of natural genetic variation in many species. Like many species with chromosomal sex determination, Drosophila females have two X chromosomes, while males have one X and one Y. The model species D. melanogaster has five roughly equally sized chromosome arms, one of which is the X chromosome. However, fusions of sex chromosomes with autosomes have occurred along the lineage leading to D. pseudoobscura and D. miranda. The resulting neo-sex chromosomes are gradually evolving the properties of sex chromosomes, and neo-X chromosomes are becoming targets for the molecular mechanisms that compensate for differences in X chromosome dose between sexes. We have previously shown that D. melanogaster possess at least tw

ORGANISM(S): Drosophila pseudoobscura

SUBMITTER: Susan Lott 

PROVIDER: E-GEOD-53483 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress