OpaR Controls a Network of Downstream Transcription Factors in Vibrio parahaemolyticus BB22

ABSTRACT: Vibrio parahaemolyticus an emerging pathogen that is a causative agent of foodborne gastroenteritis when raw or undercooked seafood is consumed. Previous microarray data using a Vibrio parahaemolyticus RIMD2210633 chip has shown the master quorum-sensing regulator OpaR controls virulence, type III and type VI secretion systems, and flagellar and capsule production genes. In a parallel study, RNA-Seq was used to comparatively study the transcriptome changes of wild type Vibrio parahaemolyticus BB22 and a ΔopaR strain directly. Differences in mRNA expression were analyzed using next generation Illumina sequencing and bioinformatics techniques to align and count reads. A comparison with the previous microarray data showed good correlation between the shared genes. The RNA-Seq offered an

ORGANISM(S): Vibrio parahaemolyticus

SUBMITTER: Roderick Jensen 

PROVIDER: E-GEOD-53639 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress