Infection of apple by Apple stem grooving virus leads to extensive alterations in gene expression patterns but no disease symptoms

ABSTRACT: To understand the molecular basis of viral diseases, transcriptome profiling has been widely used to correlate host gene expression change patterns with disease symptoms during viral infection in many plant hosts. We used infection of apple by Apple stem grooving virus (ASGV), which produces no disease symptoms, to assess the significance of host gene expression changes in disease development. We specifically asked the question whether such asymptomatic infection is attributed to limited changes in host gene expression. Using RNA-seq, we identified a total of 184 up-regulated and 136 down-regulated genes in apple shoot cultures permanently infected by ASGV in comparison with virus-free shoots cultures. As in most plant hosts showing disease symptoms during viral infection, these differenti

ORGANISM(S): Malus domestica

SUBMITTER: Ting Ye 

PROVIDER: E-GEOD-53825 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress