The miRNAome of O. viverrini induced cholangiocarcinoma by microarray:

ABSTRACT: Cholangiocarcinoma is the second most common primary hepatic malignancy worldwide, with intrahepatic cholangiocarcinoma (ICC) a particularly significant public health problem in Southeast Asia, due to its strong association with the food-borne parasite Opisthorchis viverrini (OV). This manuscript represents the first comprehensive miRNA expression profiling by microarray of the three most common histological grades of OV-induced ICC: moderately differentiated, papillary, and well differentiated tumor tissue. No cohort of miRNAs emerged as commonly dysregulated among these histological grades of OV-induced ICC. Instead, each histological grade of ICC tissue showed a distinct miRNA profile. Moderately differentiated tumor tissue showed both the greatest number and the highest magnitude of mi

ORGANISM(S): Homo sapiens

SUBMITTER: Jeffrey Bethony 

PROVIDER: E-GEOD-53992 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress