Ring1B Promotes Hepatic Stem/Progenitor Cell Expansion via Simultaneous Suppression of Cdkn1a and Cdkn2a

ABSTRACT: The expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a and Cdkn2a, demonstrating that Ring1B simultaneously regulates multiple CDKI in tissue stem/progenitor cells. Comparison of gene expression profiles between Ring1B KO and WT murine liver cells at E13.5

ORGANISM(S): Mus musculus

SUBMITTER: Yasuharu Ueno 

PROVIDER: E-GEOD-54116 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress