Genome-wide maps of HIF1a binding sites in ccRCC cell line under hypoxia condition

ABSTRACT: We report the application of chromatin immunoprecipitation and next generation sequencing technology for HIF1a binding sites at genome wide level in a RCC (renal cell carcinoma) cell line under hypoxia conditions. We found HIF1a binding sites in Caki-2 cell line under hypoxia conditions. Especially, we found HIF1a bind to SPOP under hypoxia condition, which was further validated. Examination of HIF1a binding sites in Caki-2 cell line under hypoxia condition

ORGANISM(S): Homo sapiens

SUBMITTER: Jing Zhang 

PROVIDER: E-GEOD-54327 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress