The Functional Topography of the Arabidopsis Genome is Defined by Nine Chromatin States that Associate in a Small Number of Motifs

ABSTRACT: Chromatin is of major relevance for gene expression, cell division and differentiation, among other processes. Here we have used 16 chromatin features, including DNA sequence, CG methylation, histone modifications and variants, to obtain a high-resolution landscape of the Arabidopsis chromatin states. The combinatorial complexity of chromatin features can be reduced to 9 states defined by their distinct signatures. These chromatin states preferentially associate with certain genomic elements, gene expression levels, and DNase I accessibility. Each chromatin state has strong propensity to associate with only a subset of other states defining a small number of chromatin motifs. These topographical relationships revealed that Polycomb chromatin physically separates the two heterochromatin sta

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Xiaoyu Zhang 

PROVIDER: E-GEOD-54489 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress