Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Chun Zhang
PROVIDER: E-GEOD-54630 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
BMC microbiology 20140212
<h4>Background</h4>Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an important role in Mtb persistence within macrophages. However, the mechanism of LTBI remains elusive. The aim of this study was to delineate LTBI-related miRNA expression in U937 macrophages expressing Mtb Hsp16.3 protein. U937 macrophages were infected with an integrase- ...[more]