Response of Saccharomyces cerevisiae (Dal80M-NM-^T) to linoleic acid hydroperoxide

ABSTRACT: Oxidative stress is experienced by all aerobic organisms and results in cellular damage. The damage caused during oxidative stress is particular to the oxidant challenge faced, and so too is the induced stress response. The eukaryote Saccharomyces cerevisiae is sensitive to low concentrations of the lipid hydroperoxide - linoleic acid hydroperoxide (LoaOOH) - and its response is unique relative to other peroxide treatments. Part of the yeast response to LoaOOH includes a change in the cellular requirement for nutrients, such as sulfur, nitrogen and various metal ions. The metabolism of sulfur is involved in antioxidant defence, although the role nitrogen during oxidative stress is not well understood. Investigating the response induced by yeast to overcome LoaOOH exposure, with a particula

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Patrick O'Doherty 

PROVIDER: E-GEOD-54951 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress