Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

15 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile of human osteosarcoma and modified MSCs

ABSTRACT: Analysis of gene changes in different genes modulation in MSCs and compared to primary human osteosarcoma cells Total RNA isolated from human parental MSCs and from MSCs siRB, OeMyc, SiRb-OeMyc and primary human osteosarcoma cells

ORGANISM(S): Homo sapiens

SUBMITTER: Jir-You Wang

PROVIDER: E-GEOD-56001 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Gene expression profile of human osteosarcoma and modified MSCs

Project description:Analysis of gene changes in different genes modulation in MSCs and compared to primary human osteosarcoma cells

2014-04-03 | GSE56001 | GEO

Gene expression array analysis of tumor-propagating cell populations in human osteosarcoma

Project description:Gene expression profiling of side population cells (SP) and CD146+ cells from primary human osteosarcoma. We aimed to identify genes that differentially regulated between the tumor propagating cells and the bulk tumor cells. Total RNA was isolated from SP, Non-SP(NSP), CD146+ and CD146- cells. The RNA is converted to cDNA using Nugen Ovation Kit (Nugen, CA, USA) and subjected to Illumina HT-12 array.

2016-09-01 | E-GEOD-63390 | biostudies-arrayexpress

Genome-wide analysis of transformed MSCs

Project description:Analysis of transformed MSCs at gene expression level. The aim in the present study was that overexpression of MYC in the MSCs alter gene expression of MSCs. Results provide important information of the response of overexpresion of MYCs, such as up- or down-regulated specific anabolic/catabolic cellular functions. Total RNA obtained from transformed MSCs or MSC culture cells at different passages.

2011-10-09 | E-GEOD-25296 | biostudies-arrayexpress

Nimblegen microarrays gene expression analysis of porcine transformed MSCs and sarcomas

Project description:Osteosarcoma is a relatively rare solid tumour, but the most common primary bone cancer. It predominantly affects young people and is highly malignant, requiring aggressive surgical resection and cytotoxic chemotherapy. Five-year survival for patients with metastatic osteosarcoma is only around 30% 14. We report that pigs with heterozygous and homozygous inactivation of TP53 consistently develop osteosarcomas, providing a new model of osteosarcoma at human scale to understand and treat this devastating disease. Gene expression profiling and data analysis was further described in 'A porcine model of osteosarcoma' by Anja Saalfrank et al. (2016). Differential gene expression profiles of MSCs and sarcomas relative to wild type in order to identify transcriptional changes associated with the stages of porcine MSC transformation

2016-02-23 | E-GEOD-78214 | biostudies-arrayexpress

Modulation of the osteosarcoma expression phenotype by miRNAs

Project description:This SuperSeries is composed of the following subset Series: GSE28423: Modulation of the osteosarcoma expression phenotype by miRNAs [Agilent] GSE28424: Modulation of the osteosarcoma expression phenotype by miRNAs [Illumina] Refer to individual Series

2012-10-16 | E-GEOD-28425 | biostudies-arrayexpress

Gene expression profile of modified MSCs

Project description:Analysis of gene expression changes in MSCs in response to TBX3 overexpression

2022-01-25 | GSE183848 | GEO

Comparison of gene expression profiles in rat sarcomas and masenchymal stem cells (MSCs)

Project description:To investigate the altered patways among sarcomas and MSCs, gene expression profiles were comared among rat osteosarcoma and malignant histiocytoma (MFH) to mesenchymal stem cells (MSCs) from syngeneic origin. Several altered pathways have identified including down-regulation of Wnt, Cell adhesion, ECM interaction and up-regulation of Hedgehog, cell cycling pathways in rat sarcomas compared to MSCs. Gene expression array analysis was perfromed for the samples of rat osteosarcoma COS1NR and malignant fibrous histiocytoma MFH1NR cell lines, bothe established from chemically induced tumors in F344 rats by 4-HAQO, and rat mesenchymal stem cells freshly isolated from femur bone marrow of F344 rats.

2011-10-24 | E-GEOD-33170 | biostudies-arrayexpress

Gene expression profile of modified MSCs

Project description:Gene expression profile of modified MSCs

| PRJNA762072 | ENA

Comparison of gene expression profiles in rat sarcomas and masenchymal stem cells (MSCs)

2011-10-25 | GSE33170 | GEO

Gene expression and ChIP-seq analyses of mesenchymal stem cells, osteoblasts and the U2OS osteosarcoma cell line

Project description:This SuperSeries is composed of the following subset Series: GSE27900: Gene expression analysis of mesenchymal stem cells (MSC), osteoblasts and the U2OS (osteosarcoma) cell line GSE35573: ChIP-seq analysis of H3K4Me3- and H3K27Me3-marked chromatin in mesenchymal stem cells (MSCs), osteoblasts derived from MSCs and the osteosarcoma cell line U2OS Refer to individual Series

2012-03-02 | E-GEOD-35576 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data