Effect of PARP1 inhibition on transcription in MCF7 cells

ABSTRACT: Analysis of the role of PARP1 in gene transcription in MCF7 cells under non-stress conditions. The hypothesis was that PARP1 activity in MCF7 cells plays a role in gene transcription. The results indicate that PARP1 inhibition does not significantly affect transcription after 6 hours of treatment. Total RNA was collected from MCF7 cells that had been treated with ABT-888, PJ34, Olaparib, or DMSO for 6 hours.

ORGANISM(S): Homo sapiens

SUBMITTER: Kristin Krukenberg 

PROVIDER: E-GEOD-56400 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress